HOOKE
HOOKE is a premium longevity clinic in London's West End, offering its proprietary BioPortrait diagnostic framework that combines whole-genome sequencing with polygenic risk scoring. Membership-based (from GBP 8,000/year), HOOKE targets high-net-worth individuals seeking the deepest possible biological insight for preventive action.
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Quick Overview
A genomics-forward London longevity clinic with a proprietary biological profiling framework and premium Mayfair positioning
- Physician-led : Met. A named physician is responsible for the programme, in a facility licensed to practise medicine.
- Prevention programme : Met. A longevity or prevention programme for adults without a presenting disease, offered on its own rather than as an add-on to aesthetic, surgical or single-treatment services.
- Assessment before intervention : Met. The programme starts with baseline tests (laboratory, imaging or functional) that a licensed clinician reviews with the patient, in person or remotely. Tests taken at home or at partner laboratories count.
- Plan and follow-up : Met. The patient receives a personalised plan, and the clinic stays in contact afterwards through re-testing, check-ins or follow-up consultations, even when these are optional or paid.
Care model: In person and remote · Checked
BioPortrait Assessment
1 day
HOOKE Annual Membership
12 months
About HOOKE
Founded in 2023, HOOKE is a ultra luxury outpatient longevity clinic based in London, United Kingdom. HOOKE is a premium longevity clinic in London's West End, offering its proprietary BioPortrait diagnostic framework that combines whole-genome sequencing with polygenic risk scoring. Membership-based (from GBP 8,000/year), HOOKE targets high-net-worth individuals seeking the deepest possible biological insight for preventive action.
HOOKE covers 6 of 14 core longevity capabilities tracked by World Longevity Clinics, in diagnostics and lifestyle support. The treatment menu lists 8 distinct modalities (highlights include Full Body MRI, Whole-Genome Sequencing, Polygenic Risk Scoring, Advanced Blood Panel). Our profile lists 2 programmes across day stay formats, with an indicative range of GBP 8,000 to 25,000.
HOOKE represents the genomics-forward frontier of longevity medicine in London, offering whole-genome sequencing and polygenic risk scoring as standard components of their proprietary BioPortrait assessment. The Mayfair location provides an ultra-premium patient experience, and the team's data analytics approach to longitudinal health tracking reflects a genuine commitment to turning genetic insights into actionable health strategies. The BioPortrait framework aims to create a uniquely detailed biological profile for each patient, going beyond standard biomarker panels to incorporate genomic,…
Trust & Ratings
Independent assessment from our editorial team, verified patient feedback, and public ratings.
WLC Editorial Review
Last reviewed September 2026
HOOKE represents the genomics-forward frontier of longevity medicine in London, offering whole-genome sequencing and polygenic risk scoring as standard components of their proprietary BioPortrait assessment. The Mayfair location provides an ultra-premium patient experience, and the team's data analytics approach to longitudinal health tracking reflects a genuine commitment to turning genetic insights into actionable health strategies. The BioPortrait framework aims to create a uniquely detailed biological profile for each patient, going beyond standard biomarker panels to incorporate genomic, epigenetic, and metabolic dimensions. The focus on making genetics clinically actionable, rather than just informational, distinguishes HOOKE from competitors who include genomics as an optional add-on. As a 2023 launch with a small team, HOOKE is still building its operational track record and long-term patient outcome data. The offering is heavily diagnostic, with limited therapeutic pathways available in-house. The GBP 8,000-25,000 annual membership represents a significant commitment, particularly for a clinic in its early years. For data-driven London professionals who want genomics at the center of their longevity strategy and are comfortable as early adopters of a promising new model, HOOKE offers a distinctive and intellectually rigorous approach.
"A genomics-forward London longevity clinic with a proprietary biological profiling framework and premium Mayfair positioning"
Strengths
- Whole-genome sequencing and polygenic risk scoring included as standard, not add-ons
- Proprietary BioPortrait framework provides unusually deep biological profiling
- Mayfair location with a genuinely premium patient experience
- Strong data analytics approach to longitudinal health tracking
Limitations
- Established in 2023, still building long-term patient outcome data
- Primarily diagnostic with limited therapeutic or intervention options
- Membership pricing (GBP 8,000-25,000/year) is significant for a clinic still proving its model
Data-driven London professionals who want genomics at the center of their longevity strategy, delivered with premium hospitality
Those seeking therapeutic treatments, regenerative medicine, or who prefer clinics with extensive multi-year track records
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Available Treatments & Features
Treatment Categories at HOOKE
A grouped overview of the longevity protocols offered at HOOKE, organised by clinical category and explained in plain language.
diagnostics
Diagnostic testing forms the foundation of any longevity protocol — measuring biological age, identifying disease risk before symptoms appear, and establishing baselines for tracking the effects of interventions over time.
At HOOKE: Full Body MRI, Whole-Genome Sequencing, Polygenic Risk Scoring, Advanced Blood Panel, Epigenetic Clock Testing, DEXA Scan, VO2 Max Testing.
nutritional
Nutritional protocols are personalized based on bloodwork, microbiome analysis, and genetic markers to address specific deficiencies and optimize metabolic health, energy production, and inflammatory balance.
At HOOKE: Personalized Nutrition.
Treatment Details
Full Body MRI
diagnosticsWhole-Genome Sequencing
diagnosticsPolygenic Risk Scoring
diagnosticsAdvanced Blood Panel
diagnosticsEpigenetic Clock Testing
diagnosticsDEXA Scan
diagnosticsVO2 Max Testing
diagnosticsPersonalized Nutrition
nutritionalPrograms
BioPortrait Assessment
1 day | day
Proprietary full-spectrum biological profiling combining WGS, polygenic risk, and advanced biomarkers.
HOOKE Annual Membership
12 months | day
Year-round membership with BioPortrait, quarterly biomarker tracking, and dedicated physician access.
HOOKE: Frequently Asked Questions
Detailed answers about HOOKE — what it is, where it sits in the longevity landscape, what treatments it offers, how much it costs, what to expect during a stay, and how to evaluate it against alternatives.
What is HOOKE?
HOOKE is a ultra luxury outpatient longevity clinic based in London, United Kingdom, founded in 2023. HOOKE is a premium longevity clinic in London's West End, offering its proprietary BioPortrait diagnostic framework that combines whole-genome sequencing with polygenic risk scoring. Membership-based (from GBP 8,000/year), HOOKE targets high-net-worth individuals seeking the deepest possible biological insight for preventive action. It covers 6 of 14 core longevity capabilities tracked on World Longevity Clinics, with 8 distinct treatment modalities listed in its profile.
Where is HOOKE located and how do I get there?
HOOKE is located in London, United Kingdom, and also offers remote consultations. Travel and visit details are best confirmed with the clinic through its website.
What treatments and programs does HOOKE offer?
HOOKE offers a longevity menu that includes Full Body MRI, Whole-Genome Sequencing, Polygenic Risk Scoring, Advanced Blood Panel, plus 4 additional treatment modalities listed in its full profile. Our profile lists 2 programmes in day format.
How much does HOOKE cost?
Our price range for HOOKE is GBP 8,000 to 25,000. Annual memberships from GBP 8,000/year. The final cost depends on programme or membership tier, diagnostic depth and optional treatments. Ask the clinic for a written quote tied to your programme before committing.
Who is HOOKE best suited for?
Data-driven London professionals who want genomics at the center of their longevity strategy, delivered with premium hospitality It may be a less natural fit for those who: those seeking therapeutic treatments, regenerative medicine, or who prefer clinics with extensive multi-year track records
What is the methodology behind HOOKE?
HOOKE represents the genomics-forward frontier of longevity medicine in London, offering whole-genome sequencing and polygenic risk scoring as standard components of their proprietary BioPortrait assessment. The Mayfair location provides an ultra-premium patient experience, and the team's data analytics approach to longitudinal health tracking…
How does HOOKE compare with other longevity clinics?
HOOKE sits in the ultra luxury outpatient segment, with 6/14 core longevity capabilities and a WLC Editorial Score of 78/100. Its key strengths include: Whole-genome sequencing and polygenic risk scoring included as standard, not add-ons; Proprietary BioPortrait framework provides unusually deep biological profiling. The most direct comparisons are typically other ultra luxury outpatient clinics in the same price band — see the side-by-side comparisons and alternatives pages on World Longevity Clinics for a structured assessment.
What should I expect during a visit to HOOKE?
A programme at HOOKE starts with a baseline assessment reviewed with you by a clinician. Depending on the findings, the plan can draw on lifestyle support. The programme includes a personalised plan with re-testing or check-ins afterwards.
Are the treatments at HOOKE regulated and evidence-based?
HOOKE operates under the medical regulation framework of United Kingdom under MHRA and Care Quality Commission (CQC) oversight. As a general principle, longevity medicine combines established preventive care (screening, lifestyle medicine, indicated medication) with newer protocols where the evidence is still maturing. Patients should ask any clinic — including HOOKE — to clarify which therapies are standard of care, which are off-label, and which are offered under research or experimental frameworks.
How can I book or contact HOOKE?
Bookings and program enquiries for HOOKE are typically handled through the official website at hooke.london. For an objective comparison, you can also use the comparison and alternatives tools on World Longevity Clinics to evaluate HOOKE against similar clinics before committing to a quote.
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