The Hundred Longevity House
The Hundred Longevity House is a boutique longevity destination in Tokyo's Ginza district, opened in 2024. It takes a distinctive cross-cultural approach, combining Japanese wellness traditions and food culture with Ayurvedic principles and modern regenerative medicine. NK (natural killer) cell therapy is a centerpiece offering, alongside personalized nutrition and holistic anti-aging protocols.
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Quick Overview
A visionary fusion of Japanese regenerative medicine, Ayurveda, and culinary wellness in an architecturally stunning Ginza setting
- Physician-led : Not stated on public pages. A named physician is responsible for the programme, in a facility licensed to practise medicine.
- Prevention programme : Not stated on public pages. A longevity or prevention programme for adults without a presenting disease, offered on its own rather than as an add-on to aesthetic, surgical or single-treatment services.
- Assessment before intervention : Not met. The programme starts with baseline tests (laboratory, imaging or functional) that a licensed clinician reviews with the patient, in person or remotely. Tests taken at home or at partner laboratories count.
- Plan and follow-up : Not stated on public pages. The patient receives a personalised plan, and the clinic stays in contact afterwards through re-testing, check-ins or follow-up consultations, even when these are optional or paid.
Care model: In person · Checked
Longevity Discovery
1 day
Regenerative Longevity Program
3-5 days
About The Hundred Longevity House
Founded in 2024, The Hundred Longevity House is a luxury outpatient longevity clinic based in Tokyo, Japan. The Hundred Longevity House is a boutique longevity destination in Tokyo's Ginza district, opened in 2024. It takes a distinctive cross-cultural approach, combining Japanese wellness traditions and food culture with Ayurvedic principles and modern regenerative medicine. NK (natural killer) cell therapy is a centerpiece offering, alongside personalized nutrition and holistic anti-aging protocols.
The Hundred covers 3 of 14 core longevity capabilities tracked by World Longevity Clinics, in regenerative medicine and lifestyle support. The treatment menu lists 6 distinct modalities (highlights include Advanced Biomarker Panel, NK Cell Therapy, IV Nutrient Therapy, Ayurvedic Wellness Protocols). Our profile lists 2 programmes across day and short stay stay formats, with an indicative range of JPY 550,000 to 3,000,000.
The Hundred Longevity House is one of the most architecturally ambitious longevity concepts to open recently. Spanning multiple floors of a Ginza landmark building, it combines a regenerative medicine clinic with Ayurvedic treatment rooms and a restaurant serving traditional fermented Japanese cuisine. The medical director brings impressive academic credentials from the University of Tokyo and leadership roles in Japanese regenerative medicine societies. Having an on-site cell processing center for autologous stem cell therapy is a genuine differentiator that very few clinics globally can…
Trust & Ratings
Independent assessment from our editorial team, verified patient feedback, and public ratings.
WLC Editorial Review
Last reviewed September 2026
The Hundred Longevity House is one of the most architecturally ambitious longevity concepts to open recently. Spanning multiple floors of a Ginza landmark building, it combines a regenerative medicine clinic with Ayurvedic treatment rooms and a restaurant serving traditional fermented Japanese cuisine. The medical director brings impressive academic credentials from the University of Tokyo and leadership roles in Japanese regenerative medicine societies. Having an on-site cell processing center for autologous stem cell therapy is a genuine differentiator that very few clinics globally can offer. The philosophical fusion of cutting-edge regenerative science with centuries-old Ayurvedic traditions and Japanese culinary wellness is conceptually bold and reflects Japan's unique approach to integrating tradition and innovation. With less than two years of operation, the clinic has not yet accumulated significant independent reviews or published outcome data. English-language information is limited, which presents a barrier for international patients. Pricing is not publicly available. The pedigree of the medical leadership and the quality of the physical facility suggest significant potential. For patients willing to explore a truly unique concept and who are comfortable navigating limited English resources, The Hundred offers something found nowhere else in the world.
"A visionary fusion of Japanese regenerative medicine, Ayurveda, and culinary wellness in an architecturally stunning Ginza setting"
Strengths
- Led by a former University of Tokyo professor with credentials in regenerative medicine
- On-site cell culture facility enables genuine autologous stem cell therapy
- Unique fusion of regenerative medicine, Ayurveda, and Japanese food culture
- Prestigious Ginza location in a landmark building signals serious investment
Limitations
- Opened October 2024, with very limited independent reviews or published outcome data
- English-language information is extremely limited for international patients
- No published pricing, making advance planning difficult for international visitors
Adventurous longevity seekers interested in Japanese regenerative medicine combined with traditional wellness practices in an extraordinary setting
International patients who need English-language support, published pricing, or extensive independent reviews before committing
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Available Treatments & Features
Treatment Categories at The Hundred
A grouped overview of the longevity protocols offered at The Hundred Longevity House, organised by clinical category and explained in plain language.
diagnostics
Diagnostic testing forms the foundation of any longevity protocol — measuring biological age, identifying disease risk before symptoms appear, and establishing baselines for tracking the effects of interventions over time.
At The Hundred: Advanced Biomarker Panel.
regenerative
Regenerative medicine focuses on repairing or replacing damaged tissue using the body's own biological mechanisms, including cellular therapies and growth factors that support healing and recovery at a cellular level.
At The Hundred: NK Cell Therapy, Stem Cell Therapy.
biohacking
Biohacking and recovery modalities use targeted physical interventions (cold, heat, oxygen, light, electrical stimulation) to optimize cellular metabolism, accelerate recovery, and support cognitive and physical performance.
At The Hundred: IV Nutrient Therapy.
nutritional
Nutritional protocols are personalized based on bloodwork, microbiome analysis, and genetic markers to address specific deficiencies and optimize metabolic health, energy production, and inflammatory balance.
At The Hundred: Ayurvedic Wellness Protocols, Personalized Nutrition.
Treatment Details
Advanced Biomarker Panel
diagnosticsNK Cell Therapy
regenerativeIV Nutrient Therapy
biohackingAyurvedic Wellness Protocols
nutritionalPersonalized Nutrition
nutritionalStem Cell Therapy
regenerativePrograms
Longevity Discovery
1 day | day
One-day immersive assessment combining diagnostics, NK cell consultation, and personalized Ayurvedic-Japanese nutrition plan.
Regenerative Longevity Program
3-5 days | short stay
Multi-day program with NK cell therapy, IV regenerative infusions, and holistic wellness rooted in Japanese and Ayurvedic traditions.
The Hundred Longevity House: Frequently Asked Questions
Detailed answers about The Hundred Longevity House — what it is, where it sits in the longevity landscape, what treatments it offers, how much it costs, what to expect during a stay, and how to evaluate it against alternatives.
What is The Hundred Longevity House?
The Hundred Longevity House is a luxury outpatient longevity clinic based in Tokyo, Japan, founded in 2024. The Hundred Longevity House is a boutique longevity destination in Tokyo's Ginza district, opened in 2024. It takes a distinctive cross-cultural approach, combining Japanese wellness traditions and food culture with Ayurvedic principles and modern regenerative medicine. NK (natural killer) cell therapy is a centerpiece offering, alongside personalized nutrition and holistic anti-aging protocols. It covers 3 of 14 core longevity capabilities tracked on World Longevity Clinics, with 6 distinct treatment modalities listed in its profile.
Where is The Hundred Longevity House located and how do I get there?
The Hundred Longevity House is located in Tokyo, Japan. Travel and visit details are best confirmed with the clinic through its website.
What treatments and programs does The Hundred offer?
The Hundred offers a longevity menu that includes Advanced Biomarker Panel, NK Cell Therapy, IV Nutrient Therapy, Ayurvedic Wellness Protocols, plus 2 additional treatment modalities listed in its full profile. Our profile lists 2 programmes in day and short stay format.
How much does The Hundred Longevity House cost?
Our price range for The Hundred is JPY 550,000 to 3,000,000. Regenerative and longevity programs (estimated from comparable Tokyo clinics). The final cost depends on programme or membership tier, diagnostic depth and optional treatments. Ask the clinic for a written quote tied to your programme before committing.
Who is The Hundred Longevity House best suited for?
Adventurous longevity seekers interested in Japanese regenerative medicine combined with traditional wellness practices in an extraordinary setting It may be a less natural fit for those who: international patients who need english-language support, published pricing, or extensive independent reviews before committing
What is the methodology behind The Hundred Longevity House?
The Hundred Longevity House is one of the most architecturally ambitious longevity concepts to open recently. Spanning multiple floors of a Ginza landmark building, it combines a regenerative medicine clinic with Ayurvedic treatment rooms and a restaurant serving traditional fermented Japanese cuisine. The medical director brings impressive…
How does The Hundred Longevity House compare with other longevity clinics?
The Hundred Longevity House sits in the luxury outpatient segment, with 3/14 core longevity capabilities and a WLC Editorial Score of 66/100. Its key strengths include: Led by a former University of Tokyo professor with credentials in regenerative medicine; On-site cell culture facility enables genuine autologous stem cell therapy. The most direct comparisons are typically other luxury outpatient clinics in the same price band — see the side-by-side comparisons and alternatives pages on World Longevity Clinics for a structured assessment.
What should I expect during a visit to The Hundred?
Our review of The Hundred's public pages did not find a baseline assessment reviewed with the patient by a clinician; ask who interprets your results before any treatment is recommended. Depending on the findings, the plan can draw on regenerative medicine and lifestyle support. The Hundred does not describe follow-up after the programme; ask whether re-testing or check-ins are included.
Are the treatments at The Hundred Longevity House regulated and evidence-based?
The Hundred Longevity House operates under the medical regulation framework of Japan. As a general principle, longevity medicine combines established preventive care (screening, lifestyle medicine, indicated medication) with newer protocols where the evidence is still maturing. Patients should ask any clinic — including The Hundred Longevity House — to clarify which therapies are standard of care, which are off-label, and which are offered under research or experimental frameworks.
How can I book or contact The Hundred Longevity House?
Bookings and program enquiries for The Hundred Longevity House are typically handled through the official website at thehundred.jp. For an objective comparison, you can also use the comparison and alternatives tools on World Longevity Clinics to evaluate The Hundred Longevity House against similar clinics before committing to a quote.
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Head-to-Head Page
The Hundred vs Prevention Clinic
Tokyo, Japan • 75/100 WLC Score
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