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Sex-specific longitudinal reversal of aging in old frail mice — Aging-US, 2025 Peer-reviewed

Oxytocin + Alk5 Inhibitor Combo Boosts Lifespan 70% in Elderly Mice: What the Science Actually Shows

A UC Berkeley study found that combining oxytocin with an Alk5 inhibitor extended lifespan by 70% in frail elderly male mice. Benefits were sex-specific — females showed no lasting improvement. Here's what the data says and whether it could reach humans.